Comb Reef (Knives Reef in the European version of the game) is located in Western Manoa Lai, at D-4/5. You can find epaulette sharks and octopi in between the "comb teeth". A small, hard to find hole in the rock contains a kidako moray, who is often accompanied by a cleaner wrasse. A pod of Pacific White-Sided Dolphins can be seen swimming nearby. On top of the reef, you might see several Crown-of-Thorns Starfish on top of the green plate corals found there. The Shark's Tooth Necklace is found in between the comb teeth.
Just to the East, the area known as the Entryway Slope can be found.